## Abstract An efficient avenue for the direct __N__‐arylation of nucleobases with arylboronic acids that is catalyzed by simple copper salts was discovered. The __N__‐arylnucleobases were obtained in excellent yields at room temperature within 45 min when methanol and water were used as a mixed so
Copper-Catalyzed Cross-Coupling Reactions of Nucleobases with Arylboronic Acids: An Efficient Access to N-Arylnucleobases.
✍ Scribed by Yang Yue; Zhang-Guo Zheng; Bo Wu; Chuan-Qin Xia; Xiao-Qi Yu
- Book ID
- 111699702
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 17 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A simple and efficient copper‐salt catalyzed __N__‐arylation of nucleobases is reported. In a mixed solvent of MeOH and H~2~O, the coupling products were obtained in moderate to excellent yields at room temperature within a short time. A variety of substituted __N__‐aryl nucleobases can
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