Copper-Catalyzed Amination of Aryl Halides with Aqueous Ammonia under Mild Conditions
β Scribed by Quan, Zhengjun; Xia, Haidong; Zhang, Zhang; Da, Yuxia; Wang, Xicun
- Book ID
- 121870879
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 646 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0256-7660
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π SIMILAR VOLUMES
## Abstract The __N^2^,N^2^β²__βdiisopropyloxalohydrazide/CuO system efficiently catalyzed the direct amination of aryl bromides andiodides with aqueous ammonia in water at 60 Β°C in 24 h or at 120 Β°C in only 20β30 min. Both activated and unactivated aryl and heteroaryl bromides and iodides were read
## Abstract The easy availability of the ligand, the commercially available cheap copper source, the use of a green solvent and aqueous ammonia as the readily available nitrogen source are features of this protocol.