In the presence of chiral thiourethane ligands [Cu(MeCN)4]BF4 forms active catalysts for the conjugate addition of MeMgBr, ZnEt2 and AIR3 (R = Me, Et) to non-3-en-2-one, hept-3-en-2-one, and 5-methylhex-3-en-2-one. Enantioselectivities of up to 51% are realised for these difficult substrates; for cy
Copper-Catalysed Asymmetric Conjugate Addition of Organometallic Reagents to Linear Enones
β Scribed by Simon M.W Bennett; Stephen M Brown; Anthony Cunningham; Michael R Dennis; James P Muxworthy; Michael A Oakley; Simon Woodward
- Book ID
- 108370781
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 202 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0040-4020
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Copper-Catalyzed Asymmetric Conjugate Addition of Organometallic Reagents to Linear Enones Using Thiourethane Ligands. -The conjugate addition of organometals (cf. AlMe 3 ) to simple Ξ±,Ξ²-unsaturated enones such as (I) in the presence of chiral thiourethane ligands provides the corresponding Ξ²-subst