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Copper balance and ceruloplasmin in chronic hepatitis in a Wilson disease animal model, LEC rats

โœ Scribed by Yutaka Komatsu; Yasumitsu Ogra; Kazuo T. Suzuki


Book ID
105870081
Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
145 KB
Volume
76
Category
Article
ISSN
0340-5761

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The disposition behaviors and de-coppering effect of triethylenetetramine dihydrochloride (trientine), a selective chelating agent for copper and an 'orphan drug' for Wilson's disease, have been evaluated in an animal model, Long-Evans Cinnamon (LEC) rats, and normal rats (Wistar). In LEC rats, urin