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Interactions between Zn and Cu in LEC rats, an animal model of Wilson's disease

✍ Scribed by Alessandro Santon; Sabrina Giannetto; Giacomo Sturniolo; Valentina Medici; Renata D'Incà; Paola Irato; Vincenzo Albergoni


Publisher
Springer
Year
2002
Tongue
English
Weight
312 KB
Volume
117
Category
Article
ISSN
1432-119X

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✍ Ken Iseki; Michiya Kobayashi; Ayumi Ohba; Dr. Katsumi Miyazaki; Yu Li; Yuji Toga 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 543 KB

The disposition behaviors and de-coppering effect of triethylenetetramine dihydrochloride (trientine), a selective chelating agent for copper and an 'orphan drug' for Wilson's disease, have been evaluated in an animal model, Long-Evans Cinnamon (LEC) rats, and normal rats (Wistar). In LEC rats, urin