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Copper and ceruloplasmin metabolism in the LEC rat, an animal model for Wilson disease

โœ Scribed by H. Kodama; Y. Murata; Y.D. Mochizuki; Y.T. Abe


Book ID
110222864
Publisher
Springer
Year
1998
Tongue
English
Weight
113 KB
Volume
21
Category
Article
ISSN
0141-8955

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The disposition behaviors and de-coppering effect of triethylenetetramine dihydrochloride (trientine), a selective chelating agent for copper and an 'orphan drug' for Wilson's disease, have been evaluated in an animal model, Long-Evans Cinnamon (LEC) rats, and normal rats (Wistar). In LEC rats, urin