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Coordinate regulation of stromelysin and collagenase gene expression in recessive dystrophic epidermolysis bullosa (RDEB)

โœ Scribed by Sugawara, Takamitu; Nomura, Kazuo; Nagashima, Hiroaki; Hashimoto, Isao


Book ID
123236054
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
141 KB
Volume
1
Category
Article
ISSN
0923-1811

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Expression of collagenase and stromelysi
โœ T. Sato; K. Nomura; I. Hashimoto ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 970 KB

Collagenase and stromelysin expression in recessive dystrophic epidermolysis bullosa (RDEB) was studied at both the protein and the gene expression levels in fibroblast cultures. The amount of enzyme protein in the culture medium, as determined using a specific enzyme assay, showed a 9.7-fold increa