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Cooperative binding of distamycin-A to DNA in the 2:1 mode

✍ Scribed by Fagan, Patricia; Wemmer, David E.


Book ID
118187200
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
287 KB
Volume
114
Category
Article
ISSN
0002-7863

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Accessibility of the minor groove of DNA
✍ A. F. Melnikova; A. S. Zasedatelev; A. M. Kolchinsky; G. V. Gursky; A. L. Zhuze; πŸ“‚ Article πŸ“… 1975 πŸ› Springer 🌐 English βš– 380 KB

The interaction of the antibiotics distamycin A, distamycin analogue and netropsin with chromatin of calf thymus has been studied by circular dichroism measurements and by gel filtration. The minor groove of DNA in chromatin is accessible by 83-89% to the binding of these antibiotics as compared wit