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Conversion of α-Amino Acids to Acylamido Ketones and Oxazoles

✍ Scribed by Wiley, Richard H.; Borum, Olin H.

Book ID
120990501
Publisher
American Chemical Society
Year
1948
Tongue
English
Weight
251 KB
Volume
70
Category
Article
ISSN
0002-7863

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Facile Access to N-Thiazolyl α-Amino Aci
Facile Access to N-Thiazolyl α-Amino Acids from α-Bromo Ketones and α-Amino Acids
✍ Joachim Rudolph 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 106 KB

AbstractÐN-Substituted 2-aminothiazoles are synthesized in a one-pot procedure using readily available a-bromo ketones and amines. This method is compatible with a wide range of functional groups and offers a facile and ef®cient access to the class of N-thiazolyl a-amino acid derivatives.