Conversion of diindolyl methanes to 3-vinylindoles. A simple synthesis of the indole alkaloid olivacine.
✍ Scribed by Jan Bergman; René Carlsson
- Book ID
- 104246162
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 177 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
A SII'PLE SyNRIEsIs cFTHl3lNDoIJ3ELIKAulID~. Jan w and Rem' Cdrlsson Departrnentoforganicchemistry,RayalInstituteofTechnology s-100 44 stockholnl 70, Sweden *have-tlyldevelcpeda cxmvenientsynthesisoftheanti-canCer activeindolealkaloid ellipticine (2 1 (bad on thermolysis of the readily available canpcund & 1.
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A short, new route to the title tetracyclic substructure of Sf/cycho4 alkaloids, consisting in the nucleophilic attack of an ester a-anion to a pyridinium salt, acid-induced cyclization of the resultant 1,4\_dihydropyridine, and stereospecific elaboration of the ethylidene substituent, is reported.