A biomimetic approach towards the synthesis of pumiliotoxin C has been developed.The key transformation of enamine equivalent 8 to 2 was catalyzed by contact with alumina. Cyclized intermediate 2 was then reduced stereospecifically to the trans ----decahydroquinoline 11 or stereoselectively to the c
✦ LIBER ✦
“Tandem” reactivity of 2-cyano-Δ3-piperideines: a new approach to the synthesis of ervatamine type indole alkaloids.
✍ Scribed by Jean-Luc Bettiol; Ildiko Buck; Henri-Phillippe Husson; David S. Grierson; Anna Diez; Mario Rubiralta
- Book ID
- 108381949
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 236 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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