Conversion of antibiotic A82846B to orienticin A and structural relationships of related antibiotics
β Scribed by Nagarajan, Ramakrishnan; Berry, Donnis M.; Hunt, Ann H.; Occolowitz, John L.; Schabel, Amelia A.
- Book ID
- 125851843
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 580 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0022-3263
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## Abstract A novel antibiotic, PD 121,222, was isolated from a complex of pluramycinβlike compounds containing mostly kidamycin and neopluramycin. Spectral analyses showed that this compound is the 14,16βdihydroxy analog of rubiflavin A.
This accounts for 22 carbons and 23 protons. The three missing protons belong to 3 hydroxyl groups, which was confirmed by acetylation of 1 to form a triacetate [3, m/z 528 (M+)].
In our screening studlee for new antibiotics produced by streptomycetes, a new eerie6 of basic macrollde complex, numbered YL-704, was leolated from the solvent extract of the culture filtrate of Streptomyces vlatensis var. sp. MCRL 0388. Isolated YL-704 complex was constituted by several antiblotlc