SAR studies and optimization of various modified Hygromycin A fluoroalkyl ethers, which led to the discovery of the highly potent 4'-(2-cyclopropyl-2-fluoroethyl ether) antibacterial CE-156811 (1) derived from truncation of the ribose ring and difluorination of the phenyl found in Hygromycin A, are
β¦ LIBER β¦
Application of hygromycin a structure activity relationships to the antibiotic A201A.
β Scribed by Scott J. Hecker; Susan C. Lilley; Martha L. Minich; Kim M. Werner
- Book ID
- 108477037
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 262 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0960-894X
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