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Conversion of 20α-hydroxy-4-pregnen-3-one to 20α-hydroxy-5α-pregnan-3-one and 5α-pregnane-3α,20α-diol by rat anterior pituitary

✍ Scribed by Felicia V. Nowak; Harry J. Karavolas

Book ID
118977942
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
359 KB
Volume
24
Category
Article
ISSN
0039-128X

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## Abstract 3α‐Hydroxy‐5α‐pregnane‐11,20‐dione‐2,2,3,4,4‐^2^H~5~ of 78% isotopic purity was prepared from 3α‐hydroxy‐5α‐pregnane‐11,20‐dione. The major impurity (10%) was 3α‐hydroxy‐5α‐pregnane‐11,20‐dione‐2,2,4,4‐^2^H~4~. 3α,21‐Dihydroxy‐5α‐pregnane‐11,20‐dione‐2,2,3,4,4‐^2^H~5~ 21‐acetate of 76%