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Convergent, enantiospecific total synthesis of the novel cyclodepsipeptide (+)-jasplakinolide (jaspamide)

โœ Scribed by Grieco, Paul A.; Hon, Yung Son.; Perez-Medrano, Arturo.


Book ID
126887400
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
250 KB
Volume
110
Category
Article
ISSN
0002-7863

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A practical synthesis of the peptide par
โœ Shinji Kato; Yasumasa Hamada; Takayuki Shioiri ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 163 KB

S)-Alanyl-(R)-2-bromoabryl-(R)-P-tyrosine found in jaspamide(1) was conveniently synthesized as its protected derivative 2 in good yield. Jaspamide (jasplakinolide)(l)s recently isolated from a jaspis sponge is a novel cyclodepsipeptide exhibiting potent insecticidal and antifungal activities. Recen