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A practical synthesis of the peptide part of jaspamide (jasplakinolide), a cyclodepsipeptide from a marine sponge

✍ Scribed by Shinji Kato; Yasumasa Hamada; Takayuki Shioiri

Book ID: 104217816
Publisher: Elsevier Science
Year: 1988
Tongue: French
Weight: 163 KB
Volume: 29
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)82374-6

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✦ Synopsis

S)-Alanyl-(R)-2-bromoabryl-(R)-P-tyrosine found in jaspamide(1) was conveniently synthesized as its protected derivative 2 in good yield. Jaspamide (jasplakinolide)(l)s recently isolated from a jaspis sponge is a novel cyclodepsipeptide exhibiting potent insecticidal and antifungal activities. Recent reports on synthetic studies

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