Convenient Synthetic Approach to 2,4-Disubstituted Quinazolines.
β Scribed by Serena Ferrini; Fabio Ponticelli; Maurizio Taddei
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 47 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract magnified image A novel series of 2,4βdisubstitutedβ1,2,4βtriazolo[1,5β__a__]quinazolinβ5(4__H__)βones were prepared by Dimroth rearrangement of their respective isomers namely 1,4βdisubstitutedβ[1,2,4]triazolo[4,3β__a__]βquinazolinβ5(4__H__)βones. The latter were prepared __via__ new
The preparation of 5,7-disubstituted imidazo [5,1-f ][1,2,4]triazin-4-amines, exemplified by 5-[3-(benzyloxy)phenyl]-7-cyclobutylimidazo[5,1-f ][1,2,4]triazin-4-amine, was developed through a linear and three convergent synthetic strategies, with the latter providing the greatest flexibility for div
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