Convenient synthesis of benzocyclobutene
โ Scribed by Markgraf, J. Hodge.; Basta, Salvatore J.; Wege, Peter M.
- Book ID
- 126254237
- Publisher
- American Chemical Society
- Year
- 1972
- Tongue
- English
- Weight
- 452 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
The novel homoisoflavanone scillascillin has been synthesized from phloroglucinol. The sequence described represents the first synthesis of a naturally occuring benzocyclobutene. The first example of a silyl transfer involving an 8-membered transition state is reported.
Benzocyclobutenes' have been found to be quite useful species for the synthesis of several types of compounds, including members of the alkaloid,\* steroid,3 and polycyclic ter-penoid4 classes of natural products. The key step in each of these syntheses may be rationalized in terms of a (2+4) cycloa