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Convenient synthesis of [3]catenane by olefin metathesis dimerizations

โœ Scribed by Hajime Iwamoto; Koji Itoh; Hiroyuki Nagamiya; Yoshimasa Fukazawa


Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
145 KB
Volume
44
Category
Article
ISSN
0040-4039

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Synthesis of symmetrical dimeric N,Nโ€ฒ-li
โœ Kilian Conde-Frieboes; Stina Andersen; Jens Breinholt ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 70 KB

A method has been developed for the synthesis of dimeric ligands of biological relevance on solid support using olefin metathesis as a key step. With the ruthenium catalyst used, the size of the peptide fragment did not influence the reaction. If the double bond involved was separated by at least 2