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Convenient Syntheses of m- and p-Ethynylphenols

✍ Scribed by Guo-Qiao Lai; Shi-Ling Liu; Jin-Feng Xu; Yong-Jia Shen


Book ID
101995380
Publisher
John Wiley and Sons
Year
2006
Weight
16 KB
Volume
37
Category
Article
ISSN
0931-7597

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Convenient syntheses of homopropargylgly
✍ Shouliang Dong; Lars Merkel; Luis Moroder; Nediljko Budisa πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 86 KB

## Abstract An improved classic Strecker synthesis was elaborated leading to racemic homopropargylglycine (Hpg) in 61% overall yield, while an asymmetric Strecker reaction produced Hpg and the higher homolog 2‐aminohept‐6‐ynoic acid in significantly higher yields and over 80% ee. Copyright Β© 2008 E