Preparation of 2-amino-2β²-hydroxy-1,1β²-b
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Robert A. Singer; Stephen L. Buchwald
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Article
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1999
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Elsevier Science
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French
β 280 KB
Palladium-catalyzed amination reactions were carried out with 2-triflato-2'-(4methoxybenzyloxy)-1,1'-binaphthyl (5) and benzophenone imine followed by hydrolysis of the imine and hydrogenolysis of the benzyl protecting group to afford 2-amino-2'-hydroxy-1,1'binaphthyl (1). Arylamines were also coupl