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Convenient preparation of 5'-chloro-2',5'-dideoxyadenosine

✍ Scribed by Beacham, Lowrie M.


Book ID
127292513
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
287 KB
Volume
44
Category
Article
ISSN
0022-3263

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A convenient synthesis of 2β€²,3β€²-dideoxyi
✍ I. Victor Ekhato; Jay K. Rinehart πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 191 KB

## Abstract 2β€²,3′‐Dideoxyinosine‐^13^C~5~ (ddI‐^13^C~5~) and the related 2β€²,3′‐dideoxyadenosine‐^13^C~5~ (ddA‐^13^C~5~) were prepared from (S)‐5‐[^13^C~5~]2,3‐dideoxyribonolactone 1. From a batch of this starting material ddI‐^13^C~5~ was made in 27% overall yield in seven steps and ddA‐^13^C~5~ in