Convenient and clean synthesis of imines from primary benzylamines
β Scribed by Chu, Guobiao; Li, Chunbao
- Book ID
- 118219443
- Publisher
- Royal Society of Chemistry
- Year
- 2010
- Tongue
- English
- Weight
- 141 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1477-0520
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π SIMILAR VOLUMES
The N,N-di-Boc-protected benzylamines undergo [1,2] Boc migration on treatment with KDA/t-BuOLi. By this reaction, the corresponding N-Boc-protected t-butyl esters of phenylglycines are obtained in high yields.
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A convenient method for the formation of carboxamides from carboxylic acids and primary amines in the presence of molecular sieves is described. This process is very chemoselective.