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Controlling the kinetics of interferon transgene expression for improved gene therapy

✍ Scribed by Watcharanurak, Kanitta; Nishikawa, Makiya; Takahashi, Yuki; Takakura, Yoshinobu

Book ID
127362753
Publisher
Informa plc
Year
2012
Tongue
English
Weight
706 KB
Volume
20
Category
Article
ISSN
1061-186X

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## Abstract ## Background The kinetics of gene expression from adenovirus‐based delivery vectors will be an important variable influencing the efficacy and toxicity of these vectors. As different promoters have variable strengths and kinetic profiles, the optimal dose of a therapeutic transgene pr