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Controlled release of cisplatin from lactic acid oligomer microspheres incorporating cisplatin: in vitro studies

✍ Scribed by Sakakura Chouhei; Takahashi Toshio; Hagiwara Akeo; Itoh Michitoshi; Sasabe Tsunetoshi; Lee Masaki; Shobayashi Satoshi


Book ID
113275456
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
299 KB
Volume
22
Category
Article
ISSN
0168-3659

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## Abstract Regeneration of peripheral nerves after injury is suboptimal. We now report the long term delivery of nerve growth factor (NGF) by biodegradable poly‐lactic‐__co__‐glycolic acid (PLGA) microspheres __in vitro__ and __in vivo__. Lactic to glycolic acid ratios of 50:50 and 85:15 were fabr