## Abstract An enriched population of early myeloid cells has been obtained from normal mouse bone marrow by injection of mice with sodium caseinate and the removal of cells with C3 (EAC) rosettes by FicollβHypaque density centrifugation. This enriched population had no EAC or Fc (EA) rosettes and
Control of Normal Differentiation of Myeloid Leukemic Cells to Macrophages and Granulocytes
β Scribed by Eitan Fibach, Makoto Hayashi and Leo Sachs
- Book ID
- 123651635
- Publisher
- National Academy of Sciences
- Year
- 1973
- Tongue
- English
- Weight
- 856 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/62492
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## Abstract There are three types of myeloid leukemic cells, IR^+^D^+^, IR^+^D^β^ and IR^β^D^β^. IR^+^D^+^ cells were induced to differentiate to granulocytes in mass culture in liquid medium by conditioned medium (CM) from cultures of lungs from mice injected with endotoxin. About 90% of the leuke
## Abstract D^+^ but not D^β^ myeloid leukemic cells can be induced by the appropriate conditioned medium or by serum from endotoxin treated mice, to undergo cell migration in agar, cell attachment to the surface of a Petri dish and differentiation to mature macrophages and granulocytes. Inhibition