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Contrasting glycosylation profiles between Fab and Fc of a human IgG protein studied by electrospray ionization mass spectrometry

โœ Scribed by Yusuke Mimura; Peter R. Ashton; Noriko Takahashi; David J. Harvey; Roy Jefferis


Book ID
113717425
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
804 KB
Volume
326
Category
Article
ISSN
0022-1759

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N-linked oligosaccharides were released from human and bovine polyclonal immunoglobulin G (IgG) obtained from commercial sources and also from a monoclonal IgG 1 secreted by murine B-lymphocyte hybridoma cells (CC9C10) grown under different serum-free conditions. These conditions differed according