A study of the non-covalent interaction between flavonoids and DNA triplexes by electrospray ionization mass spectrometry
β Scribed by Cuihong Wan; Meng Cui; Fengrui Song; Zhiqiang Liu; Shuying Liu
- Book ID
- 108146634
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 1008 KB
- Volume
- 283
- Category
- Article
- ISSN
- 1387-3806
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Oxidative stress and unregulated immune response are believed to play a key role in the processes inherent to Alzheimer's disease (AD). The fact that free radicals can result in neurodegeneration suggests that actions against reactive oxygen species may be beneficial in treating and pre
The recent development of electrospray ionization mass spectrometry (ESI-MS) has allowed its use to study molecular interactions driven by non-covalent forces. ESI-MS has been used to detect non-covalent complexes between proteins and metals, ligands and peptides and interactions involving DNA, RNA,
Electrospray ionization mass spectrometry has been used to study the possible non-covalent interaction between oligonucleotides and beauvericin (B) mycotoxin. Beauvericin-oligonucleotide adduct formation was observed even at low mycotoxin concentration (25 pmol/microL). Adducts were found with diffe
The detection of non-covalent complexes in the mass range 19 000-34 000 Da, using electrospray ionization mass spectrometry (ESI-MS), is reviewed. The examples discussed include (1) a protein-ligand interaction (ras-GDP), (2) an inhibitor-protein-ligand interaction (SCH 54292/SCH 54341-ras-GDP), (3)