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Construction of the Simplest Model to Explain Complex Receptor Activation Kinetics

✍ Scribed by R.P. BYWATER; A. SØRENSEN; P. RØGEN; P.G. HJORTH

Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
178 KB
Volume
218
Category
Article
ISSN
0022-5193

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✦ Synopsis

We study the mathematical solutions to the kinetic equations arising from various simple ligand-receptor [corrected] models. Focusing on the prediction of the various models for the activity vs. concentration curve, we find that solutions to the kinetic equations arising from the so-called dimer model exhibit features observed in some experiments, most noticeably a distinct maximum in the activity curve.

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