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Construction and Expression of an Enzymatically Active Form of PECAM-1 Containing the Phosphatase Domain of the Protein Tyrosine Phosphatase, SHP-2

โœ Scribed by Masaaki Noda; Cathy Paddock; Peter J. Newman


Book ID
115645834
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
206 KB
Volume
22
Category
Article
ISSN
1046-5928

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Previous studies in this laboratory have shown that the SH-2 domaincontaining protein tyrosine phosphatase SHP-1 is expressed in CNS glia and functions to modulate cytokine activities in these cells. The present study demonstrates that SHP-1 is expressed within multiple regions of the CNS in vivo, e