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Constitutive mutants for orotidine 5 phosphate decarboxylase and dihydroorotic acid dehydrogenase inSaccharomyces cerevisiae

✍ Scribed by G. Loison; R. Losson; F. Lacroute

Publisher: Springer-Verlag
Year: 1980
Tongue: English
Weight: 492 KB
Volume: 2
Category: Article
ISSN: 0172-8083
DOI: 10.1007/bf00445692

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✦ Synopsis

A mutant yeast constitutive for synthesis of both dihydroorotic acid dehydrogenase and orotidine 5' phosphate decarboxylase has been isolated. This phenotype is due to a single gene unlinked to any of the five genes of the pyrimidine pathway. This gene, called ppr1, induces the unlinked genes ural and ura3. Non-chromosomal cloned ura3 is also under the control of ppr1.

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