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Constitutive and inducible expression of cytochrome P450IA1 and P450IB1 in human vascular endothelial and smooth muscle cells

✍ Scribed by Wei Zhao; Alan R. Parrish; Kenneth S. Ramos

Publisher
Society for In Vitro Biology
Year
1998
Tongue
English
Weight
397 KB
Volume
34
Category
Article
ISSN
1475-2689

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## Abstract Transient expression of rat liver cytochrome P450IA2 cDNA was combined with the use of a shuttle vector as a mutational target to determine the frequency and types of mutation caused by the conversion of aflatoxin B, into genotoxic metabolites within human cells. Ad293 cells were first