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Expression of constitutive and inducible cytochrome P450 2E1 in rat brain

✍ Scribed by Sanjay Yadav; Alok Dhawan; Ram L. Singh; Prahlad K. Seth; Devendra Parmar

Publisher
Springer
Year
2006
Tongue
English
Weight
277 KB
Volume
286
Category
Article
ISSN
0300-8177

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The release of proinflammatory cytokines by endotoxins and during oxidative stress is considered to be an early key step in the pathogenesis of alcoholic liver disease (ALD). Ethanol-inducible cytochrome P450 2E1 (CYP2E1) has potentially pro-oxidative and toxicological properties, and its expression