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Consistent Chromosome 3p Deletion and Loss of Heterozygosity in Renal Cell Carcinoma

✍ Scribed by Gyula Kovacs, Rikard Erlandsson, Ferenc Boldog, Sigurdur Ingvarsson, Renate Müller-Brechlin, George Klein and Janos Sümegi

Book ID
123635326
Publisher
National Academy of Sciences
Year
1988
Tongue
English
Weight
869 KB
Volume
85
Category
Article
ISSN
0027-8424

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We have examined I 7 primary undifferentiated nasopharyngeal carcinoma biopsies for allelic loss on 3p, comparing the findings in tumors with those in normal lymphocyte D N A from the same patients. Ten polymorphic microsatellite markers were used between 3p I 3 and 3p26. Allelic IOU was observed in