Connexin50, a Gap Junction Protein of Macroglia in the Mammalian Retina and Visual Pathway
✍ Scribed by MICHAEL SCHÜTTE; SHUHUA CHEN; ANGELIKI BUKU; J.MARIO WOLOSIN
- Book ID
- 115605232
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 724 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0014-4835
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Retinal neurons of virtually every type are coupled by gap-junctional channels whose pharmacological and gating properties have been studied extensively. We have begun to identify the molecular composition and functional properties of the connexins that form these 'electrical synapses,' and have clo
## Abstract The vertebrate connexin gene family encodes protein subunits of gap junction channels, which provide a route for direct intercellular communication. Consequently, gap junctions play a vital role in many developmental and homeostatic processes. Aberrant functioning of gap junctions is im