Immunohistochemical localization of a gap junction protein (connexin43) in the muscularis externa of murine, canine, and human intestine
โ Scribed by H. B. Mikkelsen; J. D. Huizinga; L. Thuneberg; J. J. Rumessen
- Book ID
- 112290543
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 909 KB
- Volume
- 274
- Category
- Article
- ISSN
- 0302-766X
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Retinal neurons of virtually every type are coupled by gap-junctional channels whose pharmacological and gating properties have been studied extensively. We have begun to identify the molecular composition and functional properties of the connexins that form these 'electrical synapses,' and have clo
## Abstract Numerous studies have demonstrated a correlation between dysregulation/loss of connexin expression or gap junction intercellular communication (GJIC) function and decreased growth control both in human tumors and tumor cell lines. Likewise, restoration of constitutive connexin expressio