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Conjugal Alzheimer's disease: Is there an increased risk in offspring?

✍ Scribed by Dr. T. D. Bird; E. J. Nemens; W. A. Kukull

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
396 KB
Volume
34
Category
Article
ISSN
0364-5134

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The apolipoprotein E (ApoE) genotype is a significant risk factor and modulator of age of onset of Alzheimer's disease (AD). We analyzed the effect of the ApoE genotype in two distinct early-onset familial AD groups: families with a mutation in the presenilin-1 gene (PS-1) on chromosome 14, and fami