CONFORMATIONS OF PROLINE-CONTAINING CYCLIC PEPTIDES:
β Scribed by Hollosi, M. ;Radics, L. ;Wieland, Th.
- Book ID
- 115097316
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 355 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0367-8377
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The syntheais, CD, ir spectroscopic, and conformational studies of a series of bridged cyclic peptides of the general formula, q&[NH-(CH,),-CO-Gly-Pro-Y-Gly] (2a-d, Y = Gly or Ser(OBu'), n = 4 or 2) is reported. As indicated by difference nuclear Overhauser enhancement and Fourier transform ir exper
The 'H-nmr spectra (270 MHz) of cyclic di-and tri-~-azetidine-2-carboxylic acid [cyclo(L-Aze)z and cyclo(~-Aze)a] were determined in CDCls and DzO and computer simulated. The spectral results were compared with those obtained with cyclo(L-Pro)z and cyclo(L-Pro)3. In CDC13 and D20 solutions, the four