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Minimum energy conformations of proline-containing helices

✍ Scribed by Alexander Polinsky; Murray Goodman; Karen A. Williams; Charles M. Deber

Publisher: Wiley (John Wiley & Sons)
Year: 1992
Tongue: English
Weight: 555 KB
Volume: 32
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.360320416

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## Abstract The role of N‐terminus diproline segments in facilitating helical folding in short peptides has been investigated in a set of model hexapeptides of the type Piv‐**Xxx‐Yyy**‐Aib‐Leu‐Aib‐Phe‐OMe (Piv, pivaloyl). Nine sequences have been investigated with the following N‐terminus dipeptide