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Conformationally Restricted Hybrid Analogues of the Hormone 1α,25-Dihydroxyvitamin D3: Design, Synthesis, and Biological Evaluation

✍ Scribed by M.Christina White; Martin D Burke; Sara Peleg; Henry Brem; Gary H Posner

Book ID: 108479074
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 234 KB
Volume: 9
Category: Article
ISSN: 0968-0896
DOI: 10.1016/s0968-0896(01)00087-6

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## Noncalcemic, Antiproliferative, Transcriptionally Active, 24-Fluorinated Hybrid Analogues of the Hormone 1α,25-Dihydroxyvitamin D 3 . Synthesis and Preliminary Biological Evaluation. -New analogues (XII) of the title hormone are synthesized as mixtures of two diastereomers, which are subseque