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Conformationally constrained amino acids: enantiodivergent synthesis of all four stereoisomers of 2-(tetrahydrofuran-2-yl)glycine

✍ Scribed by Aigars Jirgensons; Maura Marinozzi; Roberto Pellicciari


Book ID
108282820
Publisher
Elsevier Science
Year
2005
Tongue
French
Weight
235 KB
Volume
61
Category
Article
ISSN
0040-4020

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The stereospecific synthesis of all four
✍ Edouard Lier; Richard Berthold; Franz Troxler πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 German βš– 534 KB

## Abstract Epoxidation of 3‐phenoxycyclohexene **5** with __m__‐chloro‐perbenzoic acid gave **6** and **7** in a ratio of 9:1. These two epoxides were heated with a series of amines to give the aminophenoxycyclohexanol derivatives **1** and **2** respectively; in all cases the reaction was regio‐