The synthesis of novel, conformationally constrained tryptophan mimetics is described.
Conformationally constrained tryptophan analogs. Synthesis of (±)-(Z)- and (±)-(E)-2-amino-2,3-methano-3-(indol-3-yl)-propanoic acids
✍ Scribed by Daniele Donati; Aaron Garzon-Aburbeh; Benedetto Natalini; Carla Marchioro; Roberto Pellicciari
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 407 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4020
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract A series of novel quinolone agents bearing a particular bulky and conformationally constrained bicyclic substituent (2,3‐dihydro‐4‐hydroxyimino‐4__H__‐1‐benzopyran‐3‐yl‐ moiety) on the piperazine ring of 7‐piperazinyl quinolones (norfloxacin, enoxacin, ciprofloxacin, and levofloxacin) w
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
The tide compounds were prepared from key intermediates readily obtained by the stereoselective Diels-Alder reaction of (Z)-2-pbenyl-4-[(S)-2,2-dimethyl-l,3dioxolan-4-ylmethylene]-5(4H)-oxazolone, a chiral az-lactone derived from (R)glyceraldehyde and cyclopentadiene.