Conformational study of a salivary proline-rich protein repeat sequence
β Scribed by Nicola J. MURRAY; Michael P. WILLIAMSON
- Book ID
- 115130647
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 714 KB
- Volume
- 219
- Category
- Article
- ISSN
- 1432-1327
No coin nor oath required. For personal study only.
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## Abstract The solid phase synthesis of a 59 amino acid human salivary protein IB7 has been accomplished using Fmoc strategy. Because the protein contains 25 proline, 13 glycine and 9 glutamine residues the coupling time, piperidine delivery and acetic anhydride reaction time were increased. Yield
The acidic proline-rich proteins ( Pr) showing genetic polymorphism were purified from human parotid salivas by gel filtration and ion exchange chromatography. Molecular weight determinations, amino acid composition analyses, and polypeplide mapping experiments indicate that the Pr 3 protein is a fr