1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose 5-phosphate to form 2-C-methyl-D-erythritol 4-phosphate, as the second step of the deoxyxylulose 5-phosphate/methylerythritol 4-phosphate pathway found in many bacteria and
β¦ LIBER β¦
Conformational Dynamics of the Flexible Catalytic Loop in Mycobacterium tuberculosis 1-Deoxy-d-xylulose 5-Phosphate Reductoisomerase
β Scribed by Sarah L. Williams; J. Andrew McCammon
- Book ID
- 111368628
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 763 KB
- Volume
- 73
- Category
- Article
- ISSN
- 1747-0277
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## Abstract The phosphonic acid derivatives such as (Xa) show potent inhibitory activity.