Conformational Analysis of l-(Alkoxymethyl)-5( R )-methyl-2-pyrrolidinone Derivatives. Determination of the Absolute Stereochemistry of Alcohols
โ Scribed by Latypov, Shamil K.; Riguera, Ricardo; Smith, Michael B.; Polivkova, Jana
- Book ID
- 127257832
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 194 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Information about the absolute stereochemistry (configuration) of some diastereomeric pairs of 28-(2alkylmorpholinyl)-3a-hydroxy-5a-pregnanes is available from the 13C chemical shifts of the C-3' and C-5' morpholine carbons. A series of anaesthetic compounds can be allocated to one group of R config
It has been reported (2) that cis-2-methyl-1-acetylcyclohexane [a] exists largely (at least -89%) in the conformation Is (rather than 58% II+ 42% Ia, approximately, assuming additivity of A-values (2,3) and ignoring other considerations), and [b] it reacts faster (33:l) towards hydroxylamine than it