Conformation of the Oligosaccharide Chain of GM1 Ganglioside in a Carbohydrate-Enriched Surface
β Scribed by Brocca, Paola; Berthault, Patrick; Sonnino, Sandro
- Book ID
- 119411637
- Publisher
- Biophysical Society
- Year
- 1998
- Tongue
- English
- Weight
- 142 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0006-3495
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π SIMILAR VOLUMES
## Abstract The solution dynamics of the oligosaccharide moiety of ganglioside G~M1~ have been determined by use of a combination of ^1^H rotating frame Overhauser effect measurements and restrained molecular dynamics simulations, It is found that the GalΞ²1β3 and NeuNAc moieties which are primarily
## Abstract __Two metabolically engineered__ Escherichia coli __strains have been constructed to produce the carbohydrate moieties of gangliosides GM2 (GalNAc__Ξ²__β4(NeuAc__Ξ±__β3)Gal__Ξ²__β4Glc; Gal=galactose, Glc=glucose, Ac=acetyl) and GM1 (Gal__Ξ²__β3GalNAc__Ξ²__β4(NeuAc__Ξ±__β3)Gal__Ξ²__β4Glc. The G