Recent studies have revealed that a dynamic axon-glial signaling occurs in the rat optic nerve, which is devoid of synapses. This interaction is postulated to be mediated by non-vesicular release of glutamate via a reversal of high-affinity glutamate transporters. Here we examined the expression of
Confocal imaging of glial cells in the intact rat optic nerve
β Scribed by A. M. Butt; K. Colquhoun; M. Berry
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 810 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0894-1491
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β¦ Synopsis
Astrocytes and oligodendrocytes in the isolated intact mature rat optic nerve have been computer imaged in three dimensions by laser scanning confocal microscopy of single cells, dye-filled with lysinated rhodamine dextran (LRD). Our results illustrate the first application of these techniques to an intact CNS white matter tract and provide comparative data for previous studies on neonatal rat optic nerve (Butt and
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