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Conditional regulation of the human CYP4X1 and CYP4Z1 genes

✍ Scribed by Üzen Savas; Mei-Hui Hsu; Keith J. Griffin; David R. Bell; Eric F. Johnson

Book ID
116177311
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
471 KB
Volume
436
Category
Article
ISSN
0003-9861

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## Abstract Hypoxic injury to the ocular surface provokes an inflammatory response that is mediated, in part, by corneal epithelial‐derived 12‐hydroxyeicosanoids. Recent studies indicate that a cytochrome P450 (CYP) monooxygenase, identified as CYP4B1, is involved in the production of these eicosan