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Differential regulation of human CYP4A genes by peroxisome proliferators and dexamethasone

✍ Scribed by Üzen Savas; Mei-Hui Hsu; Eric F Johnson

Book ID
117042263
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
272 KB
Volume
409
Category
Article
ISSN
0003-9861

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## Abstract Peroxisome proliferators cause increases in liver mass in rodents, linked to changes in cell proliferation and cell death of hepatocytes. These effects are reversible upon cessation of treatment. The underlying mechanism of the response in rodent liver is complex, but clearly dependent