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Concise Syntheses of 2-Aminoindans via Indan-2-ol.

✍ Scribed by Sueleyman Goeksu; Hasan Secen


Publisher
John Wiley and Sons
Year
2005
Weight
18 KB
Volume
36
Category
Article
ISSN
0931-7597

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Stereoselective [2,3]-wittig rearrangeme
✍ Michael H. Kress; Chunhua Yang; Nobuyoshi Yasuda; E.J.J. Grabowski πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 264 KB

An efficient, diastereoselective [2,3]-Wittig rearrangement of~x-allyloxyamide enolates has been developed using (1S,2R)-l-amino-indan-2-ol as a chiral auxiliary. After auxiliary removal, the resultant optically active a-hydroxy acids have been transformed to functionalized amino acid derivatives.